Wegovy is a prescription-only injectable medicine containing Semaglutide. It belongs to a class of drugs known as GLP-1 receptor agonists. While originally used for diabetes, it is formulated at a higher dose (2.4 mg) specifically to treat obesity and overweight conditions.
It is the first once-weekly weight loss injection approved for chronic weight management, making it a convenient and effective alternative to daily injections or fad diets.
Wegovy works by mimicking a natural hormone in your body called GLP-1 (glucagon-like peptide-1), which targets areas of the brain that regulate appetite and food intake.
It performs three key actions:
Reduces Hunger: It signals to your brain that you are “full,” helping you eat less without feeling deprived.
Slows Gastric Emptying: It keeps food in your stomach longer, prolonging the feeling of satiety after meals.
Suppresses Cravings: It quiets the “food noise” (constant thoughts about food), helping you make healthier choices effortlessly.
Most clinics don’t explain this, but following the correct “Titration Path” is the secret to success and minimal side effects.
The product comes in 5 different color-coded pens. You cannot start at the highest dose immediately. At Regions Clinic, we guide you through the official Dose Escalation Protocol to let your body adjust safely.
| Month | Dosage Strength | Goal of this Phase |
|---|---|---|
| Month 1 | 0.25 mg (Green) | Initiation: Preparing your body. Appetite reduction begins. |
| Month 2 | 0.5 mg (Pink) | Step-Up: Strengthening the effect. |
| Month 3 | 1.0 mg (Brown) | Step-Up: Significant craving control usually starts here. |
| Month 4 | 1.7 mg (Blue) | Therapeutic: You are approaching maximum efficacy. |
| Month 5+ | 2.4 mg (Black) | Maintenance: The full dose for long-term weight management. |
In the landmark STEP 1 clinical trial, it demonstrated superior results compared to other weight loss medications:
Significant Weight Loss: Adults lost an average of 15% of their initial body weight over 68 weeks.
Waist Circumference: Significant reduction in waistline and visceral fat.
Cardiovascular Health: Improvements in blood pressure, cholesterol levels, and blood sugar control.
For a patient weighing 100kg, this translates to an average loss of 15kg, significantly lowering the risk of weight-related diseases.
| Feature | Wegovy | Ozempic | Saxenda |
|---|---|---|---|
| Ingredient | Semaglutide | Semaglutide | Liraglutide |
| Max Dose | 2.4 mg (Highest) | 1.0 mg | 3.0 mg |
| Frequency | Once Weekly | Once Weekly | Daily Injection |
| Weight Loss | ~15% | ~10% | ~5-8% |
Wegovy is a FDA-Approved medical treatment, not a cosmetic “quick fix.” It is intended for adults who meet the following criteria:
BMI ≥ 30 (Obesity)
BMI ≥ 27 (Overweight) AND at least one weight-related condition, such as:
Hypertension (High Blood Pressure)
High Cholesterol (Dyslipidemia)
Type 2 Diabetes
Wegovy is a powerful tool, but it works best when your body is primed for fat loss rather than muscle loss. At Regions Clinic, our doctors recommend the “Protein-Sparing” Protocol to ensure you lose weight safely and keep it off.
1. Protein-First Nutrition
Because GLP-1 significantly reduces your appetite, your calorie intake will drop. It is critical to eat protein (lean meats, eggs, tofu) first in every meal. This prevents sarcopenia (muscle loss) and keeps your metabolism active.
2. Hydration Strategy
GLP-1 medications can slightly increase the risk of dehydration. We prescribe a minimum of 2-3 liters of water daily. Proper hydration also helps mitigate common side effects like nausea and headache.
3. Strength Retention
To achieve a toned physique rather than just a “smaller” version of yourself, we encourage incorporating resistance training (even light weights) twice a week to signal your body to burn fat stores instead of muscle tissue.
Wegovy is generally safe but does have specific contraindications. You should NOT take if:
You have a personal or family history of Medullary Thyroid Carcinoma (MTC).
You have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
You are pregnant or breastfeeding. (It is recommended to stop Wegovy 2 months before planning pregnancy).
The most common side effects are gastrointestinal (nausea, diarrhea, vomiting, constipation). These are usually mild to moderate and tend to subside as your body adjusts to the medication. This is why following our Month 1 to Month 5 titration schedule is critical to prevent discomfort.
The price of Wegovy varies depending on the dosage pen required (Initiation vs. Maintenance).
Warning: Beware of Fake Pens Due to high demand, counterfeit pens are circulating in Southeast Asia. At Regions Clinic, every box is sourced directly from the official distributor and comes with a verifiable batch number. We guarantee 100% authenticity and proper cold-chain storage.
Wegovy is designed for easy self-administration. It comes in a pre-filled pen with a hidden needle. You simply press the pen against your skin (stomach, thigh, or arm) and wait for the yellow bar to stop moving. It takes about 10 seconds and is virtually painless.
Obesity is a chronic condition. Clinical studies suggest that many patients regain weight after stopping treatment if they return to old habits. We recommend a “maintenance phase” or a gradual tapering off combined with the lifestyle changes you learned during treatment.
Yes, many patients switch from daily Saxenda to weekly Wegovy for convenience and better results. However, you cannot just “swap” them; a specific transition protocol is needed to avoid side effects. Our doctors will plan this transition for you.
